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As age begins to take its toll on the skin, we lose facial volume, which causes wrinkles to deepen. Creases develop, running from the nose to the corners of the mouth (also called nasolabial folds or laugh lines) and from mouth to chin. These creases often cause a person to look older than they are. We provide Restylane Defyne, an ideal filler that smooths deep lines and creases but maintains a range of motion to allow natural expression.


What is Restylane Defyne?

Restylane Defyne is a smooth, injectable gel, a dermal filler developed with hyaluronic acid, which is a naturally occurring substance. Restylane Defyne is a unique filler, produced with an innovative cross-linking technology called XpresHAn Technology™. This allows Restylane Defyne to smooth deep lines and creases while maintaining natural flexibility and range of facial motion.

This is how Restylane Defyne achieves a youthful, refreshed appearance without causing the face to appear stiff or forced. Defyne is particularly designed to treat deeper lines and wrinkles.

Restylane Defyne injections are minimally invasive, take about 30 minutes, and require no downtime. Results can last up to one year.

What are the benefits of Restylane Defyne?

Restylane Defyne achieves many benefits for patients with deeper lines and creases who would like to renew their appearance and achieve a natural-looking, beautiful rejuvenation.

  • Smoothed laugh lines (nasolabial folds and marionette lines)
  • Retains a range of motion, allowing natural facial expression
  • Provides facial rejuvenation
  • Safe, effective, minimally-invasive treatment
  • No downtime
  • Short treatment time
  • Results can last up to 12 months
  • Improves confidence
  • Creates naturally elegant results
Woman smiling

What happens during the procedure?

We will begin by gently cleansing your skin and preparing it for treatment. We will apply a topical anesthetic to ensure you are completely comfortable during the treatment. Restylane Defyne injections contain lidocaine, a local anesthetic that helps make the injections painless.

Dr. Sadrian will provide precise, careful injections with an ultrathin needle. The treatment achieves a natural-looking, more youthful, rejuvenated appearance. Your treatment will take around 15-30 minutes to perform. You can return to work or your usual activities as soon as the treatment is complete; the results will be apparent immediately.

Am I a good candidate for Restylane Defyne?

Patients who are unhappy with lines or creases around their nose and mouth and feel they look older than they wish to may be ideal candidates for Restylane Defyne. Candidates want a non-surgical approach to anti-aging and meet the following requirements:

  • Are not pregnant or nursing
  • Are not currently taking blood-thinners
  • Are over the age of 21
  • Are generally in good health
  • Are not allergic to the ingredients of the filler

Why choose Dr. Sadrian?

With more than 20 years of experience, Dr. Sadrian is a board-certified plastic surgeon whose long expertise with injectable treatments is one of the many reasons he is recognized as a leader in the field. His expert, gentle touch with injectables ensures his patients achieve the natural, beautifully rejuvenated appearance they hope for with Restylane Defyne. Enjoy our med spa environment–a beautiful, comfortable, welcoming space that centers around your needs and aesthetic desires.

Harbor in San Diego

Sadrian M.D.

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